
Associate Adjunct Professor
M_Surgery
+1 415 502-4658
Publications
Insights from a multi-institutional registry show duration of endocrine treatment for DCIS impacts second events.
NPJ breast cancer
Immune Subtyping Identifies Patients With Hormone Receptor-Positive Early-Stage Breast Cancer Who Respond to Neoadjuvant Immunotherapy (IO): Results From Five IO Arms of the I-SPY2 Trial.
JCO precision oncology
Hormone Receptor Positive HER2-negative/MammaPrint High-2 Breast Cancers Closely Resemble Triple Negative Breast Cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research
Multi-platform biomarkers of response to an immune checkpoint inhibitor in the neoadjuvant I-SPY 2 trial for early-stage breast cancer.
Cell reports. Medicine
Pathologic complete response (pCR) rates for patients with HR+/HER2- high-risk, early-stage breast cancer (EBC) by clinical and molecular features in the phase II I-SPY2 clinical trial.
Annals of oncology : official journal of the European Society for Medical Oncology
Regional lymph node changes on breast MRI in patients with early-stage breast cancer receiving neoadjuvant chemo-immunotherapy.
Breast cancer research and treatment
Datopotamab-deruxtecan in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial.
Nature medicine
Datopotamab-deruxtecan plus durvalumab in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial.
Nature medicine
Magnetic resonance imaging insights from active surveillance of women with ductal carcinoma in situ.
NPJ breast cancer
Cell-free DNA concentration as a biomarker of response and recurrence in HER2-negative breast cancer receiving neoadjuvant chemotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research
Epithelial Expressed B7-H4 Drives Differential Immunotherapy Response in Murine and Human Breast Cancer.
Cancer Research Communications
Association of antibiotic exposure with residual cancer burden in HER2-negative early stage breast cancer.
NPJ breast cancer
Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers.
bioRxiv : the preprint server for biology
Neoadjuvant trebananib plus paclitaxel-based chemotherapy for stage II/III breast cancer in the adaptively randomized I-SPY2 trial - Efficacy and biomarker discovery.
Clinical cancer research : an official journal of the American Association for Cancer Research
Protein signaling and drug target activation signatures to guide therapy prioritization: Therapeutic resistance and sensitivity in the I-SPY 2 Trial.
Cell reports. Medicine
Race, Gene Expression Signatures, and Clinical Outcomes of Patients With High-Risk Early Breast Cancer.
JAMA network open
B-cells and regulatory T-cells in the microenvironment of HER2+ breast cancer are associated with decreased survival: a real-world analysis of women with HER2+ metastatic breast cancer.
Breast cancer research : BCR
Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes.
Frontiers in oncology
Development and testing of a polygenic risk score for breast cancer aggressiveness.
NPJ precision oncology
Association of baseline ROR1 and ROR2 gene expression with clinical outcomes in the I-SPY2 neoadjuvant breast cancer trial.
Breast cancer research and treatment
Identifying Good Candidates for Active Surveillance of Ductal Carcinoma In Situ: Insights from a Large Neoadjuvant Endocrine Therapy Cohort.
Cancer Research Communications
Safety and efficacy of HSP90 inhibitor ganetespib for neoadjuvant treatment of stage II/III breast cancer.
NPJ breast cancer
The breast pre-cancer atlas illustrates the molecular and micro-environmental diversity of ductal carcinoma in situ.
NPJ breast cancer
Residual cancer burden after neoadjuvant chemotherapy and long-term survival outcomes in breast cancer: a multicentre pooled analysis of 5161 patients.
The Lancet. Oncology
Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2+ breast cancer in the adaptively randomized I-SPY2 trial.
Nature communications
Ganitumab and metformin plus standard neoadjuvant therapy in stage 2/3 breast cancer.
NPJ breast cancer
Tumor-Specific Major Histocompatibility-II Expression Predicts Benefit to Anti-PD-1/L1 Therapy in Patients With HER2-Negative Primary Breast Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Circulating tumor DNA and magnetic resonance imaging to predict neoadjuvant chemotherapy response and recurrence risk.
NPJ breast cancer
Predicted sensitivity to endocrine therapy for stage II-III hormone receptor-positive and HER2-negative (HR+/HER2-) breast cancer before chemo-endocrine therapy.
Annals of oncology : official journal of the European Society for Medical Oncology
Circulating tumor DNA in neoadjuvant-treated breast cancer reflects response and survival.
Annals of oncology : official journal of the European Society for Medical Oncology
Mutational profiling of micro-dissected pre-malignant lesions from archived specimens.
BMC medical genomics
Use of 18F-FDG PET/CT as an Initial Staging Procedure for Stage II-III Breast Cancer: A Multicenter Value Analysis.
Journal of the National Comprehensive Cancer Network : JNCCN
Mechanism of action biomarkers predicting response to AKT inhibition in the I-SPY 2 breast cancer trial.
NPJ breast cancer
Predictive Value of Breast MRI Background Parenchymal Enhancement for Neoadjuvant Treatment Response among HER2- Patients.
Journal of breast imaging
Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice.
Nature communications
MK-2206 and Standard Neoadjuvant Chemotherapy Improves Response in Patients With Human Epidermal Growth Factor Receptor 2-Positive and/or Hormone Receptor-Negative Breast Cancers in the I-SPY 2 Trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Surgical Standards for Management of the Axilla in Breast Cancer Clinical Trials with Pathological Complete Response Endpoint.
NPJ breast cancer
Evaluation of the HER/PI3K/AKT Family Signaling Network as a Predictive Biomarker of Pathologic Complete Response for Patients With Breast Cancer Treated With Neratinib in the I-SPY 2 TRIAL.
JCO precision oncology
DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial.
NPJ breast cancer
Gene Expression Architecture of Mouse Dorsal and Tail Skin Reveals Functional Differences in Inflammation and Cancer.
Cell reports
Adaptive Randomization of Neratinib in Early Breast Cancer.
The New England journal of medicine
Adaptive Randomization of Veliparib-Carboplatin Treatment in Breast Cancer.
The New England journal of medicine
Evolution of metastasis revealed by mutational landscapes of chemically induced skin cancers.
Nature medicine
Forty years of cancer modelling in the mouse.
European journal of cancer (Oxford, England : 1990)
Automated fluorescent detection of microsatellite instability.
Molecular biotechnology
Detection of the Replication Error Phenotype in Ovarian Cancer-PCR Analysis of Microsatellite Instability.
Methods in molecular medicine
Dependence on RAD52 and RAD1 for anticancer drug resistance mediated by inactivation of mismatch repair genes.
Current biology : CB
PCR analysis of microsatellite instability.
Methods in molecular medicine
Estrogen regulation of transforming growth factor-alpha in ovarian cancer.
The Journal of steroid biochemistry and molecular biology
Expression of the heat shock protein HSP27 in human ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
The regulation of growth and protein expression by estrogen in vitro: a study of 8 human ovarian carcinoma cell lines.
The Journal of steroid biochemistry and molecular biology
Identification of M cells and their distribution in rabbit intestinal Peyer's patches and appendix.
Cell and tissue research