Michael Campbell, PhD

Adjunct Professor
Surgery
+1 415 476-8094
Publications: 

Protein signaling and drug target activation signatures to guide therapy prioritization: Therapeutic resistance and sensitivity in the I-SPY 2 Trial.

Cell reports. Medicine

Gallagher RI, Wulfkuhle J, Wolf DM, Brown-Swigart L, Yau C, O'Grady N, Basu A, Lu R, Campbell MJ, Magbanua MJ, Coppé JP, I-SPY 2 Investigators, Asare SM, Sit L, Matthews JB, Perlmutter J, Hylton N, Liu MC, Symmans WF, Rugo HS, Isaacs C, DeMichele AM, Yee D, Pohlmann PR, Hirst GL, Esserman LJ, van 't Veer LJ, Petricoin EF

Race, Gene Expression Signatures, and Clinical Outcomes of Patients With High-Risk Early Breast Cancer.

JAMA network open

Kyalwazi B, Yau C, Campbell MJ, Yoshimatsu TF, Chien AJ, Wallace AM, Forero-Torres A, Pusztai L, Ellis ED, Albain KS, Blaes AH, Haley BB, Boughey JC, Elias AD, Clark AS, Isaacs CJ, Nanda R, Han HS, Yung RL, Tripathy D, Edmiston KK, Viscusi RK, Northfelt DW, Khan QJ, Asare SM, Wilson A, Hirst GL, Lu R, Symmans WF, Yee D, DeMichele AM, van 't Veer LJ, Esserman LJ, Olopade OI

Adrenal Neoplasms: Lessons from Adrenal Multidisciplinary Tumor Boards.

Radiographics : a review publication of the Radiological Society of North America, Inc

Chung R, Garratt J, Remer EM, Navin P, Blake MA, Taffel MT, Hackett CE, Sharbidre KG, Tu W, Low G, Bara M, Carney BW, Corwin MT, Campbell MJ, Lee JT, Lee CY, Dueber JC, Shehata MA, Caoili EM, Schieda N, Elsayes KM

Identifying Good Candidates for Active Surveillance of Ductal Carcinoma In Situ: Insights from a Large Neoadjuvant Endocrine Therapy Cohort.

Cancer Research Communications

Glencer AC, Miller PN, Greenwood H, Maldonado Rodas CK, Freimanis R, Basu A, Mukhtar RA, Brabham C, Kim P, Hwang ES, Rosenbluth JM, Hirst GL, Campbell MJ, Borowsky AD, Esserman LJ

Limited disease progression in endocrine surgery patients with treatment delays due to COVID-19.

Surgery

Collins RA, DiGennaro C, Beninato T, Gartland RM, Chaves N, Broekhuis JM, Reddy L, Lee J, Deimiller A, Alterio MM, Campbell MJ, Lee YJ, Khilnani TK, Stewart LA, O'Brien MA, Alvarado MVY, Zheng F, McAneny D, Liou R, McManus C, Dream SY, Wang TS, Yen TW, Alhefdhi A, Finnerty BM, Fahey TJ, Graves CE, Laird AM, Nehs MA, Drake FT, Lee JA, McHenry CR, James BC, Pasieka JL, Kuo JH, Lubitz CC

Modulation of the immune microenvironment of high-risk ductal carcinoma in situ by intralesional pembrolizumab injection.

NPJ breast cancer

Glencer AC, Wong JM, Hylton NM, Krings G, McCune E, Rothschild HT, Loveday TA, Alvarado MD, Esserman LJ, Campbell MJ

Characterizing the Tumor Immune Microenvironment with Tyramide-Based Multiplex Immunofluorescence.

Journal of mammary gland biology and neoplasia

Mori H, Bolen J, Schuetter L, Massion P, Hoyt CC, VandenBerg S, Esserman L, Borowsky AD, Campbell MJ

Germline genetic contribution to the immune landscape of cancer.

Immunity

Sayaman RW, Saad M, Thorsson V, Hu D, Hendrickx W, Roelands J, Porta-Pardo E, Mokrab Y, Farshidfar F, Kirchhoff T, Sweis RF, Bathe OF, Heimann C, Campbell MJ, Stretch C, Huntsman S, Graff RE, Syed N, Radvanyi L, Shelley S, Wolf D, Marincola FM, Ceccarelli M, Galon J, Ziv E, Bedognetti D

Adrenal Tumors Found During Staging and Surveillance for Colorectal Cancer: Benign Incidentalomas or Metastatic Disease?

World journal of surgery

Yanagisawa M, Malik DG, Loehfelm TW, Fananapazir G, Corwin MT, Campbell MJ

Co-expression modules identified from published immune signatures reveal five distinct immune subtypes in breast cancer.

Breast cancer research and treatment

Amara D, Wolf DM, van 't Veer L, Esserman L, Campbell M, Yau C

Characterizing the immune microenvironment in high-risk ductal carcinoma in situ of the breast.

Breast cancer research and treatment

Campbell MJ, Baehner F, O'Meara T, Ojukwu E, Han B, Mukhtar R, Tandon V, Endicott M, Zhu Z, Wong J, Krings G, Au A, Gray JW, Esserman L

The prognostic implications of macrophages expressing proliferating cell nuclear antigen in breast cancer depend on immune context.

PloS one

Campbell MJ, Wolf D, Mukhtar RA, Tandon V, Yau C, Au A, Baehner F, van't Veer L, Berry D, Esserman LJ

Biology of breast cancer in Nigerian women: a pilot study.

Annals of African medicine

Adisa CA, Eleweke N, Alfred AA, Campbell MJ, Sharma R, Nseyo O, Tandon V, Mukhtar R, Greninger A, Risi JD, Esserman LJ

Elevated levels of proliferating and recently migrated tumor-associated macrophages confer increased aggressiveness and worse outcomes in breast cancer.

Annals of surgical oncology

Mukhtar RA, Moore AP, Tandon VJ, Nseyo O, Twomey P, Adisa CA, Eleweke N, Au A, Baehner FL, Moore DH, McGrath MS, Olopade OI, Gray JW, Campbell MJ, Esserman LJ

Elevated PCNA+ tumor-associated macrophages in breast cancer are associated with early recurrence and non-Caucasian ethnicity.

Breast cancer research and treatment

Mukhtar RA, Moore AP, Nseyo O, Baehner FL, Au A, Moore DH, Twomey P, Campbell MJ, Esserman LJ

Tumor-associated macrophages in breast cancer as potential biomarkers for new treatments and diagnostics.

Expert review of molecular diagnostics

Mukhtar RA, Nseyo O, Campbell MJ, Esserman LJ

Proliferating macrophages associated with high grade, hormone receptor negative breast cancer and poor clinical outcome.

Breast cancer research and treatment

Campbell MJ, Tonlaar NY, Garwood ER, Huo D, Moore DH, Khramtsov AI, Au A, Baehner F, Chen Y, Malaka DO, Lin A, Adeyanju OO, Li S, Gong C, McGrath M, Olopade OI, Esserman LJ

Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer.

Breast cancer research and treatment

Garwood ER, Kumar AS, Baehner FL, Moore DH, Au A, Hylton N, Flowers CI, Garber J, Lesnikoski BA, Hwang ES, Olopade O, Port ER, Campbell M, Esserman LJ

Nordihydroguaiaretic acid (NDGA), an inhibitor of the HER2 and IGF-1 receptor tyrosine kinases, blocks the growth of HER2-overexpressing human breast cancer cells.

Journal of cellular biochemistry

Zavodovskaya M, Campbell MJ, Maddux BA, Shiry L, Allan G, Hodges L, Kushner P, Kerner JA, Youngren JF, Goldfine ID

Breast cancer growth prevention by statins.

Cancer research

Campbell MJ, Esserman LJ, Zhou Y, Shoemaker M, Lobo M, Borman E, Baehner F, Kumar AS, Adduci K, Marx C, Petricoin EF, Liotta LA, Winters M, Benz S, Benz CC

A call for clinical trials: lipophilic statins may prove effective in treatment and prevention of particular breast cancer subtypes.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Kumar AS, Campbell M, Benz CC, Esserman LJ

Diarylureas are small-molecule inhibitors of insulin-like growth factor I receptor signaling and breast cancer cell growth.

Molecular cancer therapeutics

Gable KL, Maddux BA, Penaranda C, Zavodovskaya M, Campbell MJ, Lobo M, Robinson L, Schow S, Kerner JA, Goldfine ID, Youngren JF

Nordihydroguaiaretic acid (NDGA) inhibits the IGF-1 and c-erbB2/HER2/neu receptors and suppresses growth in breast cancer cells.

Breast cancer research and treatment

Youngren JF, Gable K, Penaranda C, Maddux BA, Zavodovskaya M, Lobo M, Campbell M, Kerner J, Goldfine ID

In vitro anticancer activity of twelve Chinese medicinal herbs.

Phytotherapy research : PTR

Shoemaker M, Hamilton B, Dairkee SH, Cohen I, Campbell MJ

Immune dysfunction and micrometastases in women with breast cancer.

Breast cancer research and treatment

Campbell MJ, Scott J, Maecker HT, Park JW, Esserman LJ

Tid1, the human homologue of a Drosophila tumor suppressor, reduces the malignant activity of ErbB-2 in carcinoma cells.

Cancer research

Kim SW, Chao TH, Xiang R, Lo JF, Campbell MJ, Fearns C, Lee JD

Reduction of MTT by aqueous herbal extracts in the absence of cells.

Journal of ethnopharmacology

Shoemaker M, Cohen I, Campbell M

Antiproliferative activity of Chinese medicinal herbs on breast cancer cells in vitro.

Anticancer research

Campbell MJ, Hamilton B, Shoemaker M, Tagliaferri M, Cohen I, Tripathy D

Epithelial and fibroblast cell lines derived from a spontaneous mammary carcinoma in a MMTV/neu transgenic mouse.

In vitro cellular & developmental biology. Animal

Campbell MJ, Wollish WS, Lobo M, Esserman LJ

Ductal growth is impeded in mammary glands of C-neu transgenic mice.

Oncogene

Mukherjee S, Louie SG, Campbell M, Esserman L, Shyamala G

Biological therapies for breast carcinoma: concepts for improvement in survival.

Seminars in oncology

Borden EC, Esserman L, Linder DJ, Campbell MJ, Fulton AM

Vaccination with the extracellular domain of p185neu prevents mammary tumor development in neu transgenic mice.

Cancer immunology, immunotherapy : CII

Esserman LJ, Lopez T, Montes R, Bald LN, Fendly BM, Campbell MJ

Clinical trials of idiotype-specific vaccine in B-cell lymphomas.

Annals of the New York Academy of Sciences

Hsu FJ, Kwak L, Campbell M, Liles T, Czerwinski D, Hart S, Syrengelas A, Miller R, Levy R

Induction of immune responses in patients with B-cell lymphoma against the surface-immunoglobulin idiotype expressed by their tumors.

The New England journal of medicine

Kwak LW, Campbell MJ, Czerwinski DK, Hart S, Miller RA, Levy R

Interleukin 3 is a growth factor for human follicular B cell lymphoma.

The Journal of experimental medicine

Clayberger C, Luna-Fineman S, Lee JE, Pillai A, Campbell M, Levy R, Krensky AM

Ig VH gene expression among human follicular lymphomas.

Blood

Bahler DW, Campbell MJ, Hart S, Miller RA, Levy S, Levy R

Follicular lymphoma: a model of lymphoid tumor progression in man.

Annals of oncology : official journal of the European Society for Medical Oncology

Zelenetz AD, Campbell MJ, Bahler DW, Takahashi S, Oren R, Esserman L, Umetsu DT, Kwak LW, Maloney DG, Brown S

Idiotype vaccination against murine B cell lymphoma. Humoral and cellular requirements for the full expression of antitumor immunity.

Journal of immunology (Baltimore, Md. : 1950)

Campbell MJ, Esserman L, Byars NE, Allison AC, Levy R

Idiotypic variation in a human B lymphoma cell line.

Journal of immunology (Baltimore, Md. : 1950)

Berinstein N, Campbell MJ, Lam K, Carswell C, Levy S, Levy R

Immunotherapy of established murine B cell lymphoma. Combination of idiotype immunization and cyclophosphamide.

Journal of immunology (Baltimore, Md. : 1950)

Campbell MJ, Esserman L, Levy R

Synergistic antitumor activity with IFN and monoclonal anti-idiotype for murine B cell lymphoma. Mechanism of action.

Journal of immunology (Baltimore, Md. : 1950)

Basham TY, Race ER, Campbell MJ, Reid TR, Levy R, Merigan TC

Heterogeneity of a murine B cell lymphoma. Isolation and characterization of idiotypic variants.

Journal of immunology (Baltimore, Md. : 1950)

Starnes CO, Carroll WL, Campbell MJ, Houston LL, Apell G, Levy R

Idiotype vaccination against murine B cell lymphoma. Humoral and cellular responses elicited by tumor-derived immunoglobulin M and its molecular subunits.

Journal of immunology (Baltimore, Md. : 1950)

Campbell MJ, Carroll W, Kon S, Thielemans K, Rothbard JB, Levy S, Levy R

Studies on B lymphoid tumors treated with monoclonal anti-idiotype antibodies: correlation with clinical responses.

Blood

Lowder JN, Meeker TC, Campbell M, Garcia CF, Gralow J, Miller RA, Warnke R, Levy R

Importance of antibody isotype in monoclonal anti-idiotype therapy of a murine B cell lymphoma. A study of hybridoma class switch variants.

Journal of immunology (Baltimore, Md. : 1950)

Kaminski MS, Kitamura K, Maloney DG, Campbell MJ, Levy R